Author Liu, C.; Cui, Y.; Pi, F.; Cheng, Y.; Guo, Y.; Qian, H.
acemannan, considered one of the main bioactive polysaccharides of Aloe vera, possesses immunoregulation, anti-cancer, anti-oxidation, wound healing and bone proliferation promotion, neuroprotection, and intestinal health promotion activities, the biological activities of acemannan from Aloe vera determined by in vivo, in vitro and clinical experiments are summarized, and possible mechanisms of these bioactivities , use of acemannan in dentistry and wound healing, structure-activity relationships of acemannan and its medical applications, Polysaccharides are extensively used in various healthcare products and medicines because of their notable and excellent bioactivities, such as antimicrobial , antitumor antiviral, and antioxidant activities, polysaccharides are among the natural biopolymers, which are widely used as biomaterials for wound healing, drug delivery and tissue engineering , Aloe vera is one of the few natural plants that are very abundant in polysaccharides, acemannan-rich sponge was more easily absorbed than a complex inorganic material, and can also act as a scaffold to provide migration and attachment of cell growth factors, because the sponge can not only effectively fix the blood clot in orbit. Acemannan has a significant effect on the healing of alveolar bone and further promotes bone formation. This means that acemannan may be a natural biopolysaccharide material for bone regeneration
