Author Melania Casertano, Vincenzo Fogliano, Danilo Ercolinia
Nervous system disorders, beneficial effects of the probiotics on the gut and the gut-brain axis, Psychobiotics are a probiotic strain capable to affect the gut-brain axis, health-promoting properties, bioactive peptides, unsaturated fatty acids, minerals and vitamins, prebiotics, and probiotics , Bifidobacterium animalis subspecies lactis Bl-04, anti-diabetic/obese potential by Lactobacillus johnsonni 3121, Lactobacillus rhamnosus 86, and Lactobacillus casei YRL577, treatment of arthritis, pouchitis, ulcerative colitis, Crohn disease by Lactobacillus casei, Lactococcus lactis NCDO 2118, anti-cancer effects of Saccharomyces cerevisiae and engineered Escherichia coli Nissle 1917 (EcN), management of COVID-19 by Bifidobacteria (Bozkurt and Quigley 2020), and fertility improving properties of Lactobacillus plantarum 2621 , The term Psychobiotics refers to probiotics, prebiotics, and all microbiota-targeted interventions that can manipulate microbiota-gut-brain signals and have positive effects on neurological functions such as mood, cognition, and anxiety, metabolites including tryptophan and short-chain fatty acids (SCFAs), effects of SCFAs on the cellular system are mediated through immune system and endocrine pathways as well as neural and humoral route, SCFAs activate free fatty acid receptors and interact with immune and intestinal epithelial cells, which can affect the safety and function of the intestinal mucosa, microbiome profile and metabolism properties, probiotics effect mainly enhance gut health.
