Author: Choi S, Chung MH.
Aloe barbadensis Miller, immunomodulatory, antiinflammatory, UV protective, antiprotozoal, and wound- and burn-healing promoting properties, relationships between the components of aloe vera and their pharmacologic effects, promote wound, burn, and frost-bite healing, in addition to having antiinflammatory, antifungal, hypoglycemic, and gastroprotective properties, Wound healing is considered to be composed of three overlapping events: inflammation, new tissue formation, and matrix remodeling, Aloe vera gel extract stimulated fibroblast growth in a synovial model and also enhanced wound tensile strength and collagen turnover in wound tissue, topical application of aloe vera gel stimulated fibroblast activity and collagen proliferation, in addition to increasing the content of granulation tissue and tissue crosslinking by increasing the aldehyde content and decreasing the acid solubility, aloe vera gel increased levels of hyaluronic acid and dermatan sulphate in granulation tissue, formation of new tissue, angiogenesis is essentially required to provide oxygen and metabolites to the tissues. An increase in the blood supply was observed after aloe vera gel treatment, and it has been suggested that an increased oxygen access is one of the factors enhanced by aloe vera gel
