Aloe vera at the frontier of glycobiology and integrative medicine: health implications of an ancient plant. SAGE Open Medicine, 7, 2050312119875921.

bioactives are dominated by acemannan, a type of carbohydrate, and related complexes of saccharides, proteins, and lipids, management of cutaneous and some systemic conditions, such as some forms of immune dysfunction, atherogenesis, malignancy, and numerous cell functions, bioactive glycan components, diverse functional roles of glycans, moisturizing cosmetics and soothing topicals, skin products, including lotions and sun blocks, glycobiology, polymannan polysaccharides of Aloe, Intrinsic to glycobiology is glycosylation, This process is the most common form of protein and lipid modification, where saccharides are attached to proteins and lipids through a complex, but ordered, process in the ribosome, endoplasmic reticulum, and Golgi bodies of the cell to enable intracellular functioning and cell-to-cell communication, that glycoconjugates, glycolipids, glycoproteins, and proteoglycans, are critical components of the cell surface recognition process throughout all organ systems, structural diversity, glycans have the capacity to far exceed proteins and nucleic acids. Their structural diversity allows them to encode information for specific molecular recognition and to serve as determinants of protein folding, stability, and pharmacokinetics, glycosylation is one of the most common forms of posttranslational modification, glycobiology and glycosylation; the attachment of saccharide units to proteins and lipids, complex carbohydrates in cellular compartments, extracellular spaces, and body fluids, oligosaccharides, physical protection and tissue elasticity, lubrication, physical expulsion of pathogens, diffusion barriers, protection from proteases, cell migration and wound healing, modulation of membrane receptor signaling, depot (hydrophilic) functions, protection from immune recognition, epigenetic histone modifications, prebiotic support, antigen recognition, uptake and processing, and intercellular signaling.