Authors: Kenji Koizumi, MD, PhD, Megumi Hasegawa, Akira Mukaitani, Akira Yagi PhD
fermented aloe butyric and propionic acid, renal protective effect of aloe plant extract, toxins, Endophytically fermented aloe plants extract, Gastroenterology and Hepatology Research, complex and dynamic consortium of bacteria, gut microbiome plays important roles, microbiome is disturbed due to the proliferation of dysbiotic bacteria, gut bacteria generates excess amounts of potentially toxic compounds such as ammonia, amines, thiols, phenols, and indoles, but the generation of short chain fatty acids is reduced, modification of gut microbiota, harmful metabolites, beneficial metabolites such as short chain fatty acid (SCFA), Butyrate is the primary source of energy for colonocytes and is thus associated with maintenance of epithelium, colonic short-chain fatty acids (butyric, propionic and succinic acid), Microbiota-derived SCFAs, leaky gut , transporters for SCFA, transporters for SCFA, colon walls, systemic inflammation, fermentable high fiber diet, health-promoting benefits, microbiota-derived metabolites can regulate the incretin axis and mitigate inflammation via expansion of regulatory T cells, reducing the number of pathobionts , enhances intestinal motility, Long-term dietary intake of non-caloric water-soluble fiber, prebiotic activity of aloe vera juice , aloe vera gel influences the structural and activity of microorganisms in human gut
