Author: Steenkamp V, Stewart MJ.

Aloe gel, the clear jelly-like substance obtained from the parenchymatous cells in the inner leaf, Aloe gel is a familiar ingredient used in ointments and the cosmetic industries

The post Medicinal applications and toxicological activities of Aloe products. Pharm Biol. 2007; 45: 411-20. appeared first on AMB Wellness.

Author: S. Gupta

protection against radiation, anti-oxidant, anti-inflammation, aloe polysaccharides, skin moisturizers, aloe is an excellent ingredient for pros for face and hand creams, cleansers, soaps, suntan lotions, sunscreens, skin whiteners, shampoos and hair tonics, shaving preparations, bath aids, makeup and fragrance preparations to baby lotions and wipes, aloe vera component compounds, including anthraquinones, saccharides, polysaccharides, lignin, and numerous low molecular weight compounds such as vitamins and salicylic acid, bioactive maloyl glucans, synergistic action of the various components of Aloe vera gel contribute to the occurrence of a wide array of biological functions, UV-opacity potential of the gel, synergetic action between the polysaccharide moiety and other components in Aloe Gel, Skin regeneration involves inflammation, cell proliferation and contraction of collagen lattice formation, Wound healing is the process of repair and regeneration of dermis and epidermis that follows injury to the skin and other tissues of the body, macrophage activation, stimulate wound healing by increasing keratinocyte proliferation and migration , Collagen is the major protein of the extracellular matrix, and is the component which ultimately contributes to wound strength, aloe vera gel AG can inhibit matrix metalloproteinase in a dose-dependent manner, The effects of acemannan on gingival fibroblasts proliferation, keratinocyte growth factor-1 (KGF-1), vascular endothelial growth factor, type I collagen production and oral wound healing was investigated in murine model, Acemannan at 2-16 mg/ml significantly stimulated keratinocyte growth factor 1, vascular endothelial growth factor, and type 1 collagen expressions, components of AG contain mannose-6-phosphate that fits into growth receptors present on fibroblast cells and stimulates them, concept that fibroblast cells – which are key cells in forming the structure of connective tissue – possess special receptors, which are sensitive to mannose-6-phosphate and hence to mannose-containing polysaccharides, mannose-containing glycoproteins, and breakdown products derived from these large mannose rich molecules, natural antioxidants to prevent the deleterious effects of free radicals, Any imbalance in the cellular metabolism can lead reactive oxygen species (ROS) to do oxidative damage to cellular membranes or intracellular molecules

The post Cosmetic Attributes of Aloe vera L . Gel, appeared first on AMB Wellness.

Author: Narayan Prasad Yadav, Shruti Srivastava, Priyam Sinha, Debabrata Chanda*, Suaib Luqman* and Sudeep Tandon** Botany and Pharmacognosy Department, CSIR-Central Institute of Medicinal and Aromatic Plants (CIMAP)

Psoralen, cream formulation, in vitro skin permeation, vaginal, cosolvents, enhancing its transport through the skin, emulsifying agents and aqueous cream, hydroalcoholic transparent gel formulations, gelling agent, formulation excipients used in the cream and gel formulations, uniformity, viscosity, pH, stability, and limpidity, buffer Ph, penetration enhancing effect, epidermis, percutaneous flux and enhancement ratio

The post Development and evaluation of Aloe vera (L.) Burm. based topical cream formulation appeared first on AMB Wellness.

Author: Cole L, Heard C (2007)

Aloe Vera, Skin Permeation, Penetration enhancer, Permeation enhancer, Aloe Vera itself permeates the skin, Enhancement effect attributable, molecular weight of the drug in formulation, enhancing factor within Aloe Vera, permeated skin, enhancing factor and be subject to the pull effect, South African Aloe Council, Preparation of human skin membranes, Membrane release and skin diffusion studies, Tape stripping, ketoprofen, permeated through the cellulose nitrate membranes from all the 240 aloe-containing solutions, Flux, percentage ketoprofen diffused and enhancement ratio (ER) by aloe leaf materials, skin permeation, permeation 293 enhancement occurs by a ‘pull effect’

The post Skin permeation enhancement potential of Aloe vera and a proposed mechanism of action based upon size exclusion and pull effect. International Journal of Pharmaceutics 333, 10-16 appeared first on AMB Wellness.

Author: Joanna Xuan Hui Goh 1, Loh Teng-Hern Tan1,2,3*, Han Choi Yew4, Priyia Pusparajah5, Prithvy Lingham5, Chiau Ming Long6, Learn-Han Lee2,7*, Bey-Hing Goh1,7*

Moisturizers, topically applied agents, increase the moisture content in the skin to maintain skin integrity and youthful appearance, skin hydration, benefits of daily usage, moisture content and texture index of the skin, a hydrating effect, smoothness, aloe vera, stratum corneum, dermis, collagen and elastin fibers, skin plays important roles in regulating the homeostatic balance of temperature, water and electrolyte levels of the body; additionally, beneath the dermis are layers of connective tissues and adipose tissue, stratum corneum (SC), stratum granulosum, stratum spinosum, stratum basale, natural moisturizing factor (NMF), Confronting the harsh environmental challenges, moisturizing agents render a cooling effect and help to reduce the incidence of skin wear and tear caused by dryness, nature and ingredients, different moisturizers maintain hydration through different mechanisms, such as by functioning as emollients, humectants, substantives, keratolytic agents, forming an occlusive barrier to reduce water loss, Aloe barbadensis is known for its capacity to promote the healing of many skin ailments, from minor burns, cuts, frostbite, acne to more severe skin diseases and inflammation due to the fact that it can penetrate into tissues beneath the skin layers and hasten the proliferation of cells to facilitate the skin repair process, polysaccharide structure, Aloe vera is one of the natural ingredients as moisturizer, humecting effect on the skin , Humectants penetrate and draw water into the skin, skin capacitance increases with prolonged use of moisturizers ,Aloe vera gel improved moisture level in SC without altering transepidermal water loss (TEWL),The moisturizing effect of Aloe vera is likely attributed to its rich polysaccharide content, such as Acemannan and Glucomannan.

The post Hydration effects of moisturizing gel on normal skin: A pilot study. appeared first on AMB Wellness.

Author: Tyowua, A. T., Vitalis, T. B..1, Terhemen, M. M., and E. M. Mbaawuaga

Synthetic antimicrobial agents, like triclosan, used in many cosmetics are now associated with serious health problems, beginning with skin irritation, alternative antimicrobial agents, Many plant extracts have the potential to inhibit the growth of microorganisms and perhaps kill them and thus can serve as alternative antimicrobial agents in cosmetic formulations, hand-washing liquid soap, liquid soap paste, saponification vegetable oil blend , aloe vera extract can be used as an antimicrobial agent in the formulation of antimicrobial hand-washing liquid soap and other related products, rather than synthetic agents which are inherently harmful, aloe vera (Aloe barbadensis miller) contains phenolic acids/polyphenols, phytosterols, fatty acids, indoles, alkanes, pyrimidines, alkaloids, organic acids, aldehydes, dicarboxylic acids, ketones, saponins and alcohols as phytochemicals, organic antimicrobial agents in cosmetic formulations, Aloe vera extract is reported to inhibit the growth of skin pathogenic micro-organisms like Gram-positive , Staphylococcus aureus, Gram-negative, Pseudomonas aeruginosa and the fungus, Aspergillus flavus ,

The post Aloe Vera (Aloe barbadensis Miller) Extract as a Natural Antimicrobial Agent in Hand-Washing Liquid Soap. appeared first on AMB Wellness.

Authors: Wan Mohd Azizi, A. K. Azad, N.A. Ahmad

Clinical efficacy of aloe vera based products available, efficacy of skin cosmetic products, Aloe Vera is effective for skin care treatment, aloe vera as ingredient to improve skin barrier function for different skin care products formulations, emollients, occlusive and humectant. Emollients will soften and smooth the skin; occlusive provides a barrier that sits on the surface of the skin and prevents trans-epidermal water loss; and humectants, which bind and hold water in the stratum corneum, Aloe vera has a good moisturizing effect and can be used as a complement in the treatment of dry skin, mucopolysaccharides, aloe is beneficial to be used especially in dermatological aspects, It can increase the water content of the stratum corneum by attracting water from the dermis below and keeping this water bounding the stratum corneum, helps to bind moisture which will make the skin moist, TEWL, moisturizing cream, epidermal layer

The post Clinical efficacy of aloe vera based products available in the market as skin moisturiser measured by tewl value and skin hydration level by using dermalab technology appeared first on AMB Wellness.

Authors: Snehasish Dutta Gupta

Cosmetic Attributes of Aloe vera L. gel, formulation with aloe vera as skin moisturizers, face and hand creams, cleansers, soaps, suntan lotions, sun-screens, skin whiteners, shampoos and hair tonics, shaving preparations, bath aids, makeup and fragrance preparations to baby lotions and wipes, solar irradiance spectrum, ultraviolet radiation, repair and regeneration of dermis and epidermis, Skin regeneration involves inflammation, cell proliferation and contraction of collagen lattice formation, acemannan macrophage activation, Aloe polysaccharides effectively protected epithelial cells by elevating cell proliferation by inducing the progression of epidermal cells from phase G0/G1 into G2/M and S phases, restoration of tissue integrity, synthesis of the connective tissue matrix, synthesis of the connective tissue matrix. Collagen is the major protein of the extracellular matrix

The post Cosmetic attributes of Aloe vera L. gel appeared first on AMB Wellness.

Authors: M. Imran Qadir

Aloe vera has the property of diminishing the pigmentation and dark, spots on the face, cellular regeneration, anti-bacterial and anti-fungal activities of Aloe vera make it useful for skin eruption, Aloe vera is very valuable for skin disorders, Aloe vera also provides relief from itching and also helps to treat blisters, Aloe vera initiates the synthesis of elastin as well as collagen. These proteins are essential for preventing the aging of the skin, Aloe vera helps to eradicate acne scars by performing as an immune booster and an anti-inflammatory agent, Aloe vera impart the sensation freshness. It helps in increasing distribution of blood therefore providing easier oxygen exchange among the cells, hence giving them nourishment, Aloe Vera has an outstanding possession in diminishing the hurting of sunburn, Aloe vera gel, cream or lotion applied on the face forms a delicious cover that helps to shield the skin from dust and other natural elements which may be injurious to the skin

The post Medicinal and cosmetological importance of Aloe vera appeared first on AMB Wellness.

Author: Irene Dini and Sonia Laneri

green cosmetics, ecology and sustainability, environmentally friendly creams, makeup, and beauty products, hoping that they are not harmful to health and reduce pollution, body beauty is linked to well-being, both external and internal, skincare products, Nutricosmetics, combines the benefits derived from food supplementation with the advantages of cosmetic treatments to improve the beauty of our body, protect the skin from the aging action, improved skin quality (both aesthetic and histological), bioactive molecules used in nutricosmetic formulations, phytochemical analyses, natural/organic, ingredients derived from plants, green products, organic ingredients, National Organic Program (NOP), beauty supplements, botanical extracts improve personal care , plants as active ingredients in cosmeceuticals and nutricosmetics formulations, Plant cell culture consent to produce high-value ingredients (primary and secondary metabolites), Natural antiaging ingredients include barrier repair, moisturizing, anti-inflammatory, skin lightening, and sunblock agent, skin moisturizing agents can be emollients, occlusives, and humectants, Emollients cover the skin with a protective film to hydrate and soothe it, contribute to decreasing flaky skin and roughness, Barrier Repair Agents, skin barrier stops trans epidermal water loss and defends against pathogens , Barrier repair agents are the essential fatty acids, phenolic compounds, tocopherols, phospholipids, cholesterol, and ceramide, Skin Lightening Agents, Skin lightening agents decrease the concentration of melanin (skin’s pigment), skin tone is lighter when there is less melanin. Skin whitening agents act as inhibitors of the tyrosinase (a key enzyme in melanogenesis) and/or melanosome transfer (pigment granules in the melanocytes, contained in the basal layer of skin epidermis), Sunblock Ingredients UV radiation is divided into three main categories: UV-A (320–400 nm), UV-B (280–320 nm), and UV-C (100–280 nm), based on the wavelength. Elevated exposure to UV radiation can cause edema, erythema, hyperpigmentation, photoaging, immune suppression, and skin cancer based on the intensity and range of UV radiation, Skin Antioxidant Systems, Reactive oxygen species (ROS) are atoms or molecules whose last electronic layer contains unpaired electrons and molecules of excited oxygen, Molecular oxygen, hydrogen peroxide, and singlet oxygen are not free radicals but start oxidative reactions and make free radicals, aloe vera produces a skin-lightening effect, inhibits melanogenesis, and decreases tyrosinase and DOPA polymerase actions, Mucopolysaccharides and the amino acid profile of Aloe vera (e.g., arginine, histidine, threonine, glycine, serine, and alanine) improve water retention in the stratum corneum , Aloe gel has antioxidant properties. It enhances the metallothionein, superoxide dismutases, and glutathione peroxidase activities in skin-cells act. Aloe makes the skin elastic and reduces wrinkles, improving elastin and collagen production by fibroblasts, Aloe gel has wound-healing effects. It keeps the wound moist, reduces the inflammation process, and enhances the epithelial cell migration and rapid maturation of collagen, Aloe gel promotes hair growth through pilosebaceous

The post The New Challenge of Green Cosmetics: Natural Food Ingredients for Cosmetic Formulations, appeared first on AMB Wellness.