Author Sasan Khadem nematollahi1 , Abbas Pardakhty2, Kobra Habibi3 , Mitra Mehrabani3
effectively deliver these biologicals, Niosomes are vesicles composed of non-ionic surfactants, which are biodegradable, relatively nontoxic, more stable and inexpensive, an alternative to liposomes, application in medicine, preparation of niosome, types of niosomes, characterisation and their applications, Bilayer, drug entrapment, lamellar, niosomes, surfactants, targeted drug delivery, designed for attempting to concentrate the drug in the tissues of interest while reducing the relative concentration of the medication in the remaining tissues, Different carriers have been used for targeting of drug, such as immunoglobulin, serum proteins, synthetic polymers, liposome, microspheres, erythrocytes and niosomes, self-assembly of non-ionic surfactants into vesicles, hydration are microscopic lamellar structures formed upon combining non-ionic surfactant of the alkyl or dialkyl polyglycerol ether class with cholesterol, encapsulated glucomannan in vesicles, release of the polysaccharides, Encapsulation efficiencies, Niosomes could be used for topical delivery of Aloe gel due to slow diffusion-based release rate of Aloe gel and the high stability of the prepared vesicles. Lipid vesicles have penetration enhancing properties, hopefully resulted in better efficacy of the gel in topical administration, Glucomannan
