Author Anthony J Bilotta, Yingzi Cong
regulation of host homeostasis, composition and function of the microbiota, saturated fats, bacterial metabolites of dietary fiber, short chain fatty acids (SCFAs), healthy microbiome, epithelial and immune cell functions in the intestines, therapeutic application, host defense, Ulcerative colitis, Crohns disease, acetate, propionate, and butyrate ,role for gut microbiota metabolites in modulating intestinal homeostasis and immunity, with dietary fibers and their bacterial fermentation products, short chain fatty acids (SCFAs), playing an essential part, bacterial fermentation of dietary fibers, colonic cells, SCFA absorption occurs by three mechanisms: passive diffusion, electroneutral, or electrogenic uptake, SCFAs are able to stimulate mucus production, SCFAs stimulate antimicrobial peptides , SCFAs regulate the daily turnover of the epithelial lining and regulate stem cell proliferation, SCFA regulation of tight junctions, SCFAs and immune regulation, SCFA regulation of neutrophils, SCFA regulation of T lymphocytes, SCFA regulation of macrophages, SCFA regulation of dendritic cells,