Author Tai-Nin Chow J, Williamson DA, Yates KM, Goux WJ.
Acemannan, an acetylated ?-1,4-linked glucomannan, Aloe vera gel carbohydrate, act as an immunostimulant, displaying adjuvant activity on specific antibody production [15] and enhancing the release of interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis fator-? (TNF-?) and interferon-? (INF-?) [22], Release of these cytokines stimulates an increase of up to 300% in the replication of fibroblasts in tissue culture and enhances macrophage phagocytosis, Proliferation of fibroblasts is known to be responsible for healing burns, ulcers and other wounds of the skin and gastrointestinal lining, adjuvant activity on specific antibody production, Carbohydrate composition, glycans, ability to activate macrophages and T cells