Authors V Kusum Devi 1, Nimisha Jain, Kusum S Valli
Biocompatibility. A measure of how a biomaterial interacts in the body with the surrounding cells, tissues and other factors. A biomaterial is considered to have good biocompatibility if it does not generate a vigorous immune response, resists build-up of proteins and other substances on its surface that would hinder its function, and is resistant to infection. Drug Delivery Systems. Engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Routes of Delivery. Medications can be taken in a variety of waysby swallowing, by inhalation, by absorption through the skin, or by injection. Each method has advantages and disadvantages, and not all methods can be used for every medication. Improving current delivery methods or designing new ones can enhance the use of existing medications. novel drug delivery technology is applied in herbal medicine, it may help in increasing the efficacy and reducing the side effects of various herbal compounds and herbs. This is the basic idea behind incorporating novel method of drug delivery in herbal medicines. modern phytopharmaceutical research can solve the scientific needs (such as determination of pharmacokinetics, mechanism of action, site of action, accurate dose required etc.) of herbal medicines to be incorporated in novel drug delivery system, such as nanoparticles, microemulsions, matrix systems, solid dispersions, liposomes, solid lipid nanoparticles and so on. medicinal product on the market have to be accompanied by a dossier containing particulars and documents relating in particular to the results of physico-chemical, biological or microbiological tests as well as pharmacological and toxicological tests and clinical trials carried out on the product and thus proving its quality, safety and efficacy and an acceptable level of safety. Herbal medicinal product: any medicinal product, exclusively containing as active ingredients one or more herbal substances or one or more herbal preparations, or one or more such herbal substances in combination with one or more such herbal preparations; Herbal substances: All mainly whole, fragmented or cut plants, plant parts, algae, fungi, lichen in an unprocessed, usually dried, form, but sometimes fresh. Certain exudates that have not been subjected to a specific treatment are also considered to be herbal substances. Herbal substances are precisely defined by the plant part used and the botanical name according to the binomial system ; Herbal preparations: preparations obtained by subjecting herbal substances to treatments such as extraction, distillation, expression, fractionation, purification, concentration or fermentation. These include comminuted or powdered herbal substances, tinctures, extracts, essential oils, expressed juices and processed exudates. oral, external and/or inhalation preparation. herbal substance, the indication, the specified strength and the posology, the route of administration and any other information necessary for the safe use of the herbal substance as a traditional medicinal product. innovative forms to delivery drugs with herbal excipients as aloe vera, formulation design with final drug product design. We offer end-to-end support for various topical delivery routes, including dermal, nasal/lung, ophthalmic, otic, vaginal/rectal, and ungual. Dermal Delivery. topical and transdermal products, dermatological formulations, develop skin penetration enhancer, optimize formulation design and target engagement against established and customer specific biochemical pathways with range of semi-solid dosage forms including creams, gels, sprays, foams, ointments, lotions, mousses and lacquers, transdermal patches, drug in adhesive to multi-layer. Lung & Nasal Delivery, develop and characterize aloe as vehicle through devices for delivery to the nasal cavity and lung for MDI, DPI and nebulizer formulations. Drug delivery via these routes is attracting growing attention with the dietary supplements, nutrition health and herbal medicine market industry in the space of inhalation formulation development, according with EU regulation for drug delivery products, formulations, and devices in models, optimizing the chances of market success. Development of lung and nasal delivery development. Ophthalmic Delivery. The eye is a complex organ with unique anatomy and physiology, and it can be difficult to overcome its natural protective barriers and aloe as bioenhancer can be effective vehicle for drugs, develop drops, lotions and injectables covering conjunctival, corneal, intravitreal and transscleral routes of delivery, develop specific models for measuring trans-corneal penetration, and optimize formulations and understand the fate of products applied without having to run in vivo trials. Oro-mucosal, Rectal and Vaginal Delivery. Skin enhancement develops a wide range of formulations optimized for mucosal membrane treatment including creams, gels, ointments, suppositories, foams, sprays, lotions, lozenges and films, commercial topical, intravitreal (intra-ocular) and trans-scleral (peri-ocular) herbal products for both immediate and controlled release, Otic Delivery. Developed specific drops, lotions and other topicals for treating outer and middle ear conditions with aloe vera, drops and foams, both of which are effective formulations for treating the ear canal. Ungual and Trans-ungual Delivery. Development drugs for ungual and transungual drug delivery, these products cover a wide range of formulations for treating nails including creams, gels, sprays, lotions, and lacquers.
