Author: Meisam Shokraneh, G. Ghalamkari, M. Toghyani, N. Landy
risk of bacteria resistance to specific antibiotics possibly by continuous subtherapeutical administration of antibiotic growth promoters (AGPs) in poultry feed led to a ban on the use of AGP in poultry production, aloe vera is alternative substances for poultry growth promotion and disease prevention, effect of water supplementation of Aloe vera (AV) as an AGP substitute on performance, intestinal microflora, and immune responses of broilers, 1% Aloe Vera gel in drinking water, Body weight of broilers supplemented with different levels of Aloe Vera increased compared with control group, broiler, ileal microflora, immune responses, performance, continuous use of in-feed antibiotics is suspected to result in common problems such as increasing resistance of pathogens to antibiotics , accumulation of antibiotic residues in animal products and the environment, and imbalance of normal microflora, aloe vera is a natural additives, Aloe polysaccharides , humoral immune response and cellular immunity, acemannan activate macrophages to release inflammatory cytokines such as interleukin-1 (IL-1), IL-6, and tumor necrosis factor-? (TNF-?), Aloe Vera gel has demonstrated antimicrobial properties against a wide range of pathogenic bacteria such as Staphylococcus aureus and Escherichia coli, AV gel on intestinal microflora and immunity in broiler chickens, positive effects of AV relative weight of lymphoid organs of broilers, AV on performance, intestinal microflora, and immune responses in broilers, Aloe Vera gel on broiler growth performance and other important biomarkers for broiler development and health such as carcass characteristics, ileal microflora, and humoral immunity when it is supplemented in drinking water.