Author Karolina Chilicka , Iwona Dzie ´ndziora-Urbi ´nska , Renata Szygu?a Binnaz Asanova and Danuta Nowicka
microbiome; skin microflora; probiotics; skin care, Acne vulgaris is a disease characterised by skin eruptions such as whiteheads, blackheads, pustules, papules, and cysts, inflammatory lesions, Topical agents, microbiome (microbiota) describes the entirety of microorganisms present in a given habitat, Bacterial composition depends on the use of cosmetics, environmental factors, profession, exposure to UV radiation, antibiotics, and humidity, dysfunction of the skin barrier function, surface of the skin, proper immunity of the organism and defence by microorganisms, thus determining tolerance to substances supplied to the human body with food, leading to an immune response, microbiota also modifies the production of short-chain fatty acids (SCFAs), which fulfil many functions, e.g., nourishing intestinal cells and modulating brain activity, propionic acid, Externally Used Probiotics in Dermatology and Cosmetology, probiotic effects are Lactobacillus and Bifidobacterium, Probiotics may be used product categories such as drugs, cosmetics, dietary supplements, and food and food additives, The International Cooperation on Cosmetics Regulation (ICCR) developed categories of microbiome-related products that included probiotics and postbiotics, . The action of probiotics is based on binding them to the epidermal surface, inhibiting pathogens, producing antimicrobial substances, and increasing immunomodulatory properties. Immunomodulatory properties transformthe probiotic cosmetic into a preparation that can be used in the case of dermatological skin diseases, deep moisturising effect, stimulating the production of lipids, and repair processes in the epidermis, These probiotics have a deep moisturising effect, stimulating the production of lipids, and repair processes in the epidermis, the number of unfavourable pathogens is eliminated or reduced, the production of toxic metabolites is reduced, the production of antibodies is increased, the homeostasis of the immune system is restored, and the synthesis of the cytokines is regulated.
