Author: Marta Sánchez, Elena González-Burgos, Irene Iglesias, and M. Pilar Gómez-Serranillos*
Aloe vera, treat skin injuries (burns, cuts, insect bites, and eczemas) and digestive problems because its anti-inflammatory, antimicrobial, and wound healing properties, mechanism of action, identifying the compounds responsible for these activities, acemannan, pharmacological studies (in vitro, in vivo, and clinical trials) of aloe vera gel, new pharmacological data research, studies refer to anti-cancer action, skin and digestive protective activity, and antimicrobial properties, Clinical trials with aloe vera, study the clinical effect of relevant metabolites in different human conditions and pathologies, bone protection, cancer, and diabetes, Aloe barbadensis Miller, Aloe vera has shown other therapeutic properties including anticancer, antioxidant, antidiabetic, and antihyperlipidemic. Aloe vera contains more than 75 different compounds, including vitamins (vitamin A, C, E, and B12), enzymes (i.e., amylase, catalase, and peroxidase), minerals (i.e., zinc, copper, selenium, and calcium), sugars (monosaccharides such as mannose-6-phosphate and polysaccharides such as glucomannans), anthraquinones (aloin and emodin), fatty acids (i.e., lupeol and campesterol), hormones (auxins and gibberellins), and others (i.e., salicylic acid, lignin, and saponins), peer-reviewed scientific journals of the Pubmed database, acemannan Digestive Diseases Protection, increase of Pulp cell proliferation , ALP, Type I collagen, BMP-2, BMP-4, vascular endothelial growth factor and dentin sialoprotein expresión, Aloe polysaccharide, JAK2 and STAT-3 expression JAK2, p-JAK2, STAT-3 and p-STAT3 protein expression, Ulcerative colitis protection, Aloe vera extract, Cell viability, Aloe polysaccharide Skin Protection, TNF-? levels , ? IL-8 and IL-12 expression levels, p65 expression, IkB-alpha protein expression, Psoriasis protection, Aloe vera, Cell viability, Cell proliferation, Cell migration, Wound healing, Photodamage, Membrane integrity, maintenance, Lysosomal stability, TFG?1 and bFGF, factor expression, Cell number, Keratinocyte proliferation and differentiation, Cell surface expression of adhesion molecules (?1-integrin, ?6-integrin, ?4-integrin and E-cadhesin), Corneal epithelial cell wound closure (Aloe vera concentrations ? 175 ?g/mL),Type IV collagen-degrading activity , Aloe vera extract 200 X Aloe vera extract 200:1, CD25 and CD28 expression , Suppression of T cell proliferation, IL-2, IFN-? and IL-17A secretion, Aloe polysaccharide Anticancer Effects , ULK1 mRNA expression, BECN1 and BCL-2 mRNA expression, Acemannan Anti-Inflammatory Activity, Human gingival fibroblasts, IL-6 and IL-8 expression, NF-??/DNA binding, Peripheral blood mononuclear cells, MCF-7 cells and HeLa cells, Apoptosis induction, Cyclin D1, CYP1A1 and CYP1A2, Bax and p21 expression, Hamster pancreatic ?-cell line HIT-T15 in response to free fatty acids, Number of apoptotic ?-cell death, Relief of endoplasmic reticulum stress signaling, Antioxidant Properties, Lactobacillus and Bifidobacterium species, Human fecal bacteria, Bacterial growth (fructans), Bifidobacterium spp population, Acetate concentrations, H1N1 subtype Influenza A virus, H1N1 subtype influenza, virus replication, Viral adsorption period
