Author Patel , Chopra , Simran Chaurasia
As per Biopharmaceutical Classification System (BCS), one of the main concerns is low solubility and/or permeation of drugs resulting in reduced absorption and poor bioavailability, to overcome these issues, various strategies have been adopted, including the use of permeation enhancers which are also known as bioenhancers, bioenhancers are synthetic or natural compounds that increase the bioavailability of drugs and nutrients such as vitamins, amino acids, minerals, etc., into the systemic circulation and at the site of action for exhibiting improved therapeutic action, by improving bioavailability, bioenhancers can reduce drug dose, decrease the treatment period, and circumvent the problem of drug resistance, plant based bioenhancers can serve as a better alternative owing to their natural origin, plant-based bioenhancers have been used in a wide variety of antibiotics, antiviral, and anti-cancer therapeutics, these can be categorized based on their sources and mechanism of action