Author Mariano Del Toro-Barbosa, Alejandra Hurtado-Romero, Luis Eduardo Garcia-Amezquita, and Tomás García-Cayuela
gut-brain-microbiota axis bilateral communication system that enables gut microbes to interact with the brain, and the latter with the gut, Gut bacteria influence behavior, depression and anxiety symptoms are directly associated with alterations in the microbiota, Psychobiotics are defined as probiotics that confer mental health benefits to the host, psychobiotic potential, psychobiotic potential of several bacterial strains and fermented products, restore mental health, life quality, depression decrease productivity at work, serious mood disorder, sad and anxious mood, pessimism, irritability, fatigue, alterations in sleeping patterns, and suicidal thoughts, interaction of psychological, environmental, genetic, and biological factors, intestinal and mental disorders coexisting, central nervous system and the gastrointestinal tract, central nervous system and the gastrointestinal tract, gut microbiota exerts, enteric microbiome plays a key role in the gut-brain axis communication, involvement of neural, endocrine, immune, and metabolic systems, cognitive functions, alterations in the microbiota, Gut microbial dysbiosis is often connected to aberrant immune responses that include the overproduction of inflammatory cytokines, calibrate the innate and adaptive responses, metabolites they produce can pass through this barrier and enter and accumulate in the hosts circulatory system, where they are able to stimulate cells from the immune system
