Author Prajakta N. Dongare, Anuja S. Motule, Mahesh R. Dubey, Manisha P. More, Prerna A. Patinge , Ravindra L. Bakal and Jagdish V. Manwar
Ethno-botanical information of such plants and their usage by indigenous cultures is useful in the conservation of traditional system of medicine, biodiversity, to promote health care system, therapeutic effects, Novel drug delivery systems for delivery of herbal drugs possesses several advantages over conventional formulations, an optimum amount of the concerned drug is administered to the patient in such a way that it reaches exactly the site of action and produce therapeutic effects, some drugs have an optimum concentration range within which maximum benefit is derived, and concentrations above or below this range can be toxic or produce no therapeutic benefit at all, to minimize drug degradation and loss, to prevent harmful side-effects and to increase drug bioavailability and the fraction of the drug accumulated in the required zone, various drug delivery and drug targeting systems are currently under development Novel drug delivery system is a new approach to drug delivery, In novel drug delivery technology; control of the distribution of drug is achieved by incorporating the drug in carrier system or in changing the structure of the drug at molecular level, novel drug delivery systems possess following advantage, enhancement of solubility, increased bioavailability, protection from toxicity, enhancement of pharmacological activity, enhancement of stability, Improved tissue macrophages distribution, sustained delivery, protection from physical and chemical degradation, Herbal formulation means a dosage form consisting of one or more herbs or processed herb(s) in specified quantities to provide specific nutritional, cosmetic benefits, and/or other benefits meant for use to diagnose treat, mitigate diseases of human beings or animals and/or to alter the structure or physiology of human beings or animals, Herbal preparations are obtained by subjecting whole plant, fragmented or cut plants, plants parts to treatments such as extraction, distillation, expression, fractionation, purification, concentration or fermentation. These include comminuted or powdered herbal substances, tinctures, extracts, essential oils, expressed juices and processed exudates, actual amount of the drug may not reach the blood. If the drug doesn’t reach the blood at a minimum level which is known as ‘minimum effective level’ then there will be no therapeutic effect, Modern phytopharmaceutical research can solve the scientific needs such as determination of pharmacokinetics, mechanism of action, site of action, accurate dose required, novel herbal drug delivery system includes different types of formulations such as liposomes, phytosomes, pharmacosomes, niosomes, nanoparticles, microspheres, transferosomes, ethosomes, transdermal drug delivery system and proniosomes, Transdermal delivery system provides the advantage of controlled drug delivery, enhanced bioavailability, reduction in side effects and easy application
