Author R. Sfriso,M. Egert,M. Gempeler,R. Voegeli,R. Campiche
human skin microbiome, dermatological and cosmetic fields, skin microbiota, collection of vital microorganisms living on our skin, maintain its delicate balance is an essential step to gain insight into the mechanisms responsible for healthy skin and its appearance, development of approaches which preserve or restore the natural, individual balance of the microbiota represents a novel target not only for dermatologists but also for skincare applications, skincare segment to help restoring and balancing the structure and functionality of the skin microbiota, hair follicles and sweat ducts, main skin function is to maintain homeostasis by preventing water and extracellular fluid loss (permeability barrier), by keeping a constant body temperature, healthy-looking human skin also harbours resident or transient viruses, skin surface depends on physiological characteristics (pH, temperature, sebum content and moisture (linked to the presence of sweat and sebaceous glands distributed across the skin)), topography (rough or smooth surface of the corneocytes) as well as on exogenous environmental factors such as UV exposure, temperature and humidity and it is reflected in a differential microbial colonization, skin conductance and transepidermal water loss (TEWL), differential microbial colonization , stratum corneum, the skin-resident microbiota guarantees protection and a biological barrier, skin microbiota composition, Damaged skin barrier with dysbiosis, skin pH, dendritic epidermal T cells.
