Author M. E. Morales, V. Gallardo, B. Clares, M. B. Garcia, and M. A. Ruiz
Cellulite, a clinical syndrome mainly affecting women, involves specific changes in conjunctive dermic and subcutaneous tissue, leading to vascular and hypertrophic alterations in adipose tissues and the consequent alteration of tissue structure, design of hydrogels and pluronic-lecithin organogels elaborated as vehicles of Aloe vera (Aloe vera barbadensis miller) and Hydrocotyle asiatica (Centella asiatica) for the treatment of cellulite, hydrogels show better organoleptic characteristics than organogels, rheological point of view, both hydrogels and organogels display a plastic behavior. However, the main difference between the two is that the more complex internal structure of the organogel bestows it with more viscosity. Finally, in vitro tests with Franz-type diffusion cells revealed that the release of cosmetic active principle from the tested excipients was appropriate, both in terms of magnitude and velocity.
